Conditions Treated by Pediatric Stem Cell Transplantation

Cancer (Oncology)

Leukemia

• Acute myelogenous leukemia
• Acute lymphoblastic leukemia
• Chronic myelogenous leukemia
• Juvenile myelomonocytic leukemia
• Myelodysplastic syndrome

Lymphoma

• Non-Hodgkin’s lymphoma
• Hodgkin’s disease

Neuroblastoma

Solid Tumors

• Wilms tumor
• Brain tumors
• Bone and soft tissue sarcoma
• Germ cell tumor

Hematology

Bone marrow failure

• Severe aplastic anemia
• Congenital aplastic anemia
• Fanconi anemia
• Diamond Blackfan anemia (DBA)
• Severe congenital neutropenia

Hemoglobinopathies

• Thalassemia
• Sickle cell disease
• Paroxysmal nocturnal hemoglobinuria

Leukocyte disorders

• Chronic granulomatous disease
• Leukocyte adhesion deficiency
• Chediak Higashi syndrome

Immunological disorders

• Severe combined immunodeficiency (SCID)
• Wiskott Aldrich syndrome
• IPEX syndrome
• Hyper IgM syndrome
• ADA deficiency
• Bare lymphocyte syndrome
• Ommen syndrome
• CD40 ligand deficiency
• DOCK8 deficiency
• Hyper IgE syndrome
• X-linked lymphoproliferative syndrome
• Hereditary lympohistocytosis
• STAT1 gain of function
• Autoinflammatory syndromes
• 22q11 deletion syndrome (DiGeorge syndrome)

Genetic diseases

• Adrenoleukodystrophy
• Mucopolysacchraidosis I (Hurlers Disease)
• Metachromatic leukodystrophy
• Gauchers Disease
• Mucopolysaccharidosis VI (Maroteaux-Lamy)
• Pyruvate Kinase Deficiency
• Schimke immuno-osseous dysplasia (SIOD)